Tag: 南京夜网梧桐

Let the record show

first_imgDear Editor,In Stabroek News of April 8, 2019, there was an opinion piece from one GKH Lall which sought to instruct Mr Mohamed I Ali (executive member of the PPP) upon which plank he should jump. What campaign is Mr GKH Lall talking about?There can be no official campaign until general elections are called by Mr Lall’s candidate, Mr David Granger. It was Mr GHK Lall who said in the 2015 campaign that Mr Granger was polite and acceptable (see interview with Chris Ram) and offered his support to him. That is his right as a dual citizen and voter and beneficiary of the Treasury, thanks to his political and economic sponsors in the PNC. But please do not play with the people’s intelligence and pretend that you mean well for Mr Mohammed I Ali or the people of Guyana.This nation is yet to see the outcome of this politeness that Mr Lall was referring to in 2015. Is the word polite now being re-defined by Mr Lall? Is it polite to ignore the Guyana Constitution and not follow the rule of law? Is it polite to unilaterally impose on the nation a GECOM Chairman who has revealed himself as nothing else but a political apparatchik of Congress Place? Is it polite to supervise the greatest acts of corruption in the history of Guyana that took place between 2016 and 2019 and not do a thing as Executive President? Is it polite to be untruthful to the youths by stealing more than 30,000 jobs for them in three years in defiance of your promises in 2015?I was in Guyana in March 2019 and asked Mr Mohammed I Ali some hard questions. One of those questions was – Why are you (Mr Ali) not more on TV explaining your policy measures? In his wisdom, this was his answer. He asked me – Has an elections date been announced?Mr Ali further told me that at this time he is listening directly to the ordinary people in the villages and urban wards of Guyana on a 1-2-1 basis. His mission right now is to use the data gathered from those conversations to craft a menu of human development policies which can be launched swiftly once his party wins power. The common theme he is hearing is the need to create new jobs sustainably and this is what he plans to do when the occasion presents itself. He outlined for me in detail how he is going to create these 50,000 jobs over 5 years and from my international experience, I am convinced in my conviction that it is highly possible.What it needs is proper programme management of the plan, which is a skill set sorely lacking in Team Granger. So what appears like rocket science to these inexperienced and incompetent minds in Team Granger, is what the rest of the world is doing every second of the day – creating new jobs.When I was a Project Manager on a CDB Project, I had a chance to observe Mr Ali’s skill set and from what I saw, he is a person who has real project management competence and skills, unlike Mr Granger. This skillset served him well when he accelerated and project managed the PPP’s most successful public policy – housing. What the PPP did was to expand the stock of land available for housing by over 100,000 house lots in under 20 years. More than half of those lands now have real homes on them with real families in those homes who are on a pathway to building real new wealth with their real equity. That is the sort of human development that continues to evade these friends of Mr GHK Lall.I was advised that Mr Ali will be telling his story nationally when Mr Lall’s candidate, Mr Granger (who has now been certified after 3 years as a human development failure), calls the elections. Until such time, Mr Ali told me he plans to continue with his original plan – deepening his direct bond with the masses.Let me share a real-life example. When I visited Berbice in March 2019, two village teams told me they wanted to meet Mr Ali. I telephoned him and the very next day he was walking in those mixed Guyanese villages listening to the plight of the people and even sat down under a bottom house and had a meal with one of the families.So there is a method to the strategy and let the record speak, Mr Mohammed I Ali is not alone in this struggle to ensure that democracy is kept alive. There are thousands of us who are working tirelessly to protect this democracy won by Dr Jagan in 1992. Let the record show, history and time are on Mohammed I Ali’s side. Can we say the same for Mr GHK Lall and friends in Congress Place?Yours faithfully,Sasenarine Singhlast_img read more

World’s Smallest Rotary Engine Highlighted

first_imgThe smallest rotary motor in the world keeps your body humming.  It also keeps bacteria, plants, polar bears, giraffes, salmon, sea urchins and just about everything else humming.  It’s a nano-wonder called ATP synthase.  This molecular motor has been reported many times in these pages, but not recently; what’s new?  The state of our knowledge about ATP synthase was summarized in a paper in Nature by three German scientists.1  Basically, it’s a fascinating machine, but there’s still a lot more to learn.    It’s not just figurative speech to call ATP synthase a rotary motor.  It actually generates torque (the subject of the paper in Nature).  The authors compared it to a Wankel engine – the kind that powers a Mazda car, and used the word “motor” 30 times in the paper.  They said the first studies of this molecular machine revealed it “resembling a three-chambered molecular Wankel engine, therefore strongly suggested that rotation, rather than alternation, was nature’s choice, and that the synthesis of ATP might be mechanically driven by rotation….”  Synthesis of ATP (thus the name) is its job.  ATP (adenosine triphosphate) is the energy currency for all of life.  The ATP molecule is a nucleotide with extra phosphate groups attached.  It requires energy to attach the phosphate groups; energy is liberated when they are removed.  Most molecular processes in the cell (and in all of life) use that liberated energy that comes from ATP.  Plants use it for photosynthesis; animals use it for respiration.  Quadrillions of these rotary engines in a human body manufacture ATP constantly, day and night, to keep those processes operational.  If they suddenly stopped, you would be dead before you hit the floor.    ATP synthase has several parts; a rotor, a stator, and a camshaft.  It’s actually two motors in one.  The top half (called F1) is a three-chambered assembly factory that pushes the phosphates onto the nucleotide.  Three pairs of lobes in this stepping motor turns loading ADP and phosphate, assembling them, and releasing ATP molecules.  They are powered underneath by a waterwheel-like rotating motor that runs on proton motive force (see 12/22/2003).  Taking advantage of the ever-present Brownian motion and electrostatic interactions, the protons turn the wheel.  This simultaneously turns a coupled camshaft-like mechanism that protrudes into the top half, which transfers the torque to the ATP-assembling lobes.  The engine can work in either direction, constructing ATP molecules or breaking them down, depending on the concentration gradient.     Scientists have been intrigued by the mismatch of gear ratios between the top and bottom halves of the engine.  In some animals, for instance, there are 11 units in the rotating half, but 3 in the top half.  This implies some transfer of elastic energy in the camshaft.  Whatever is happening, it works: scientists say this machine approaches 100% efficiency.  For a taste of the discussion from the paper for those who know physics, they are discussing the match between the energy needed for ATP hydrolysis and the mechanical work done by the motor:The match implies 100% efficiency for the conversion of the Gibbs free energy of ATP hydrolysis into mechanical work performed on the elastically strained filament.  This is not surprising given the approximate thermodynamic equilibrium of the enzyme (long)-filament construct.  It is more informative to say that there is no slip between ATP hydrolysis in F1 and rotation in FO under the given conditions.2  Rotary slip in FOF1 in chloroplasts and bacteria has been detected, but only under single-site occupancy, that is, at nucleotide concentrations significantly below 100 nM.  The momentary torque can be larger (for example, during a particular power stroke) or smaller (during a kinetic dwell) than its equilibrium average.  This may account for the still puzzling independence of the torque from the ATP concentration in the nanomolar to millimolar range (see ref. 2 for a review).  It is worth mentioning that the other technique for determining the torque from the rate of rotation underestimates its magnitude because it neglects viscous flow coupling between the filament and the enzyme-supporting surface.The mismatch of gear ratios may actually make the machine more efficient.  “It has also shown that an elastic power transmission is indispensable for a high rate of coupled turnover under load,” they said.  “It increases the rate by several orders of magnitude over that of a rigidly coupled double motor….. The elastic power transmission both increases the ‘kinetic efficiency’ of the coupled motors … and allows the double motor to function with different gears in different organisms.”    In conclusion, they noted five questions about ATP synthase that remain to be answered since the true mechanical nature of this rotary engine came to light around 1997 (and won its discoverers the Nobel Prize).  Surrounding those questions were expressions of marvel at the design of this machine:ATP synthase (FOF1) is a molecular machine that combines the electrical, mechanical and chemical aspects of enzyme function.  These are neatly separated, readily attributed to its different subunits, and reasonably well understood thanks to a wealth of structural and kinetic data.  However, understanding the enzyme fully at a molecular level will require considerable efforts, both experimental and theoretical.  There are five outstanding issues…. Only when we have solved these problems will we come close to a full understanding of this remarkable piece of cellular machinery.There are other examples of rotary engines in living cells, including the bacterial flagellum (which is an order of magnitude larger), and helicases (the machines that unwind DNA).  There are also two other spinoffs of ATP synthase (if you’ll pardon the pun), built on the same principle, that perform other functions (see 02/24/2003 and 12/22/2003 for information on of them).  Most other cellular machines, like the actins and kinesins, operate in a linear fashion.  “The coupled operation of two rotary motors, one electrical (FO) and one chemical (F1), is unique,” the authors said.  “In FOF1-ATPase there is no fine-tuning of the two stepping motors;3  instead, their coupled operation is smoothed and speeded by elastic power transmission, which accounts for its high kinetic efficiency and robust function..”  Scientists used to believe life was incapable of utilizing the wheel.  Now they know better.  Speaking of elastic power transmission producing high kinetic efficiency and robust function, they mentioned something that should tempt a biophysicist to investigate: “Other nanomotors probably share this feature.”1.  Junge, Seilaff and Engelbrecht, “Torque generation and elastic power transmission in the rotary FOF1-ATPase,” Nature 459, 364-370 (21 May 2009) | doi:10.1038/nature08145.2.  F0 refers to the rotating part of the machine that runs on proton motive force.  F1 refers to the top half that synthesizes ATP.3.  They refer not to design principles but to the non-integer gear ratio between the two parts which, as they explained, actually increases the yield by an order of magnitude.  See also the 08/10/2004 entry: “ATP Synthase: Another Unexpected Case of Fine Tuning”.We could form a pretty large stack of scientific papers with the following characteristics: (1) they express marvel at the engineering design of living things, and (2) they say absolutely nothing about evolution.  This paper was another prime example.  Somebody should make a project of that and carry the stack to school board meetings where the NCSE is giving their usual spiel that nothing in biology makes sense except in the light of evolution.    The more you know about ATP synthase, the more you will be led to conclude that this is a wondrous device showcasing intelligent design.  It’s mechanically perfect, irreducibly complex, 100% efficient, absolutely necessary for life, and capable of generating awe among scientists who study it.  Notice that it was discovered 138 years after Charlie dreamed up his little myth about how design could invent itself.(Visited 111 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

Ernie Els joins golfing legends

first_imgNot content with merely being a golfinggreat, Els also has a golf developmentfoundation, a project that raises fundsfor autism, a course design company and a successful wine farm.(Image: Ernie Els) Despite his imposing height of 1.91m,Els is known for his genial personality.(Image: Wikimedia Commons) MEDIA CONTACTS • Duncan WoodsBrand manager, Els Group (SA)+27 21 881 3588 RELATED ARTICLES • SA to host world’s richest golf event • SA golf prodigy wins British Open • Sun City golf courses still top notch • Reviving sport in SA schoolsSource: SouthAfrica.infoSouth African sporting great Ernie Els was inducted into the World Golf Hall of Fame on Monday. He joins the legendary Gary Player, who entered the Hall in 1974.The other members of the 2011 Hall of Fame class were Jock Hutchison, Doug Ford, Jumbo Ozaki, Frank Chirkinian, and former US president George Bush.Nicknamed “The Big Easy” because of his wonderful swing, Els was elected in his first year on the ballot. That’s not surprising as he has won 62 titles so far in his career, including two US Opens and one British Open title. Much like Player, he has enjoyed success around the world.Success around the worldEls has won 15 times on the PGA Tour, 21 times on the European Tour, 18 times on South Africa’s Sunshine Tour, and recorded eight other wins besides. He has also played in the Presidents Cup six times, represented South Africa in the Dunhill Cup in nine consecutive years, and in the World Cup five times.He topped the European Tour’s Order of Merit in 2003 and 2004. He has also won the World Matchplay Championship a record seven times. Gary Player is tied with Seve Ballesteros for the second most wins, with five.Long before he turned professional, Els began making his mark and his name first sprung to prominence in 1984 when he won the 1984 Junior World Golf Championship in San Diego by beating home town golfer Phil Mickelson in the final. It has indeed been a long journey.Impact beyond the golf courseHis impact, however, extends beyond his achievements on the course. South African golf is going through a purple patch at present, with Charl Schwartzel the current Masters champion and Louis Oosthuizen the British Open champion. Both of them were members of Els’ junior golf foundation, now known as the Ernie Els and Fancourt Foundation.Oosthuizen told Helen Ross on the PGA Tour website: “If it weren’t for Ernie Es, I would not be where I am today. It’s as simple as that.“I spent several happy years at Ernie’s foundation and whenever I wanted help since I have been out on Tour, Ernie has happily given it. I could not have found a better role model.”‘A great inspiration’Schwartzel said: “Ernie has been a great inspiration and friend to me for years. He is always happy to give his time and expertise, and I have been the grateful beneficiary of his generosity.”It is not only the younger generation of South African golfers that appreciates what Els has done. Gary Player, too, was full of praise for him.“I was so pleased to hear the news that Ernie has been selected to be inducted into the World Golf Hall of Fame,” he said. “Ernie certainly deserves this recognition, as he epitomises a ‘world’ golfer.“He is a credit to the game and an ambassador for the sport. Ernie has been a wonderful friend over the years and I am very fond of him and his family.”Champion for autismApart from his excellence as a golfer and the opportunities he has created for youngsters through his foundation, Els is also striving to make a difference in the lives of people who have autism, or who are affected by it.Duncan started with the Ernie Els Wines team in 2003, and has recently re-joined the group as Ernie Els Group Brand Manager focussing on the South African market.His son Ben is autistic and Els has used his profile to raise money for charities devoted to the condition, whilst also establishing the Els for Autism Foundation.In 2009, he hosted the first annual Els for Autism charity golf event, which featured many PGA Tour and Champions Tour players. That year, he raised $725 000 (R4.9-million) for the Renaissance Learning Center, a non-profit school for autistic children, near his residence in West Palm Beach, Florida.The pace of fund raising at the charity golf event has been maintained, and after it was recently held for a third time the money raised by it had topped $2.2-million (R14.9-million).Els Center for ExcellenceEls, along with his wife Liezl, has established the Els Center for Excellence which, it is planned, will combine the Renaissance Learning Center with a research facility. It is a $30-million (R203-million) project and the couple has committed $6-million R41-million) of their own money to it.To top things off, mention must be made of Els as a successful golf course designer, with top class layouts in Asia, Europe, the Middle East, the Americas and southern Africa. They include, among others, the Savannah course at Mission Hills in China, the re-design of Wentworth in England, The Durrat al Bahrain in Bahrain, The Els Club in Dubai, Hoakalei in Hawaii, and Oubaai in South Africa.last_img read more

OSIA/OSWP award nominations due June 1

first_imgShare Facebook Twitter Google + LinkedIn Pinterest In 2010, the Ohio Sheep Improvement Association (OSIA) Board of Trustees initiated an award nomination program to recognize outstanding accomplishments made by sheep farmers as well as people who are associated with the Ohio sheep industry. Nominations for these awards can only be submitted by OSIA members and must be received by June 1, 2016.Award recipients will be honored at the 2016 Buckeye Shepherd’s Symposium. If you would like to nominate someone for any of these awards, please contact the OSIA Office at 614-246-8299 or rhigh@ofbf.org for an application. Award applications will also be posted at www.ohiosheep.org after April 1, 2016.Nominations are being accepted for the following categories. Information and requirements regarding these awards will be available with the award application:Charles Boyles Master Shepherd AwardFriend of the Ohio Sheep Industry AwardDistinguished Service AwardEnvironmental Stewardship Award.last_img read more

2019 Paulding County Annual Meeting

first_imgShare Facebook Twitter Google + LinkedIn Pinterest 2019 Paulding County Annual MeetingThe 2019 Annual Meeting was held at the Paulding County Fairgrounds Saturday, Sept. 14, 2019. Dinner was catered by Puckerbrush Pizza, with delicious BBQ.Celebrating 100 years of Ohio Farm Bureau!After dinner, the business meeting was held, board members and delegates were elected, and prizes were won!Jessica Vandenbroek gave the organization director’s report and presented scholarships, Rose Hartschuh gave the state trustee report, and board President Ryan McClure gave the county report and recapped the year.Birthday cake was enjoyed and games were played, celebrating 100 years of Ohio Farm Bureau and the 2019 year in Paulding County.last_img read more

Private universities in UP to be governed by umbrella act

first_imgThose looking to set up private universities in Uttar Pradesh will be required to submit an undertaking that the varsity will not get involved in “anti-national activities of any sort.”The varsities would also have to submit that they would not allow such activities to take place on their premises or in the name of the varsity.Such acts will be considered a violation of the conditions provided for the setting up of the universities and would authorise the State government to take action according to the relevant legal provisions.The above provisions are part of the conditions laid down by the Uttar Pradesh Private Universities Ordinance, 2019 that was approved by Yogi Adityanath’s Cabinet on Tuesday.As per a government press note, national integration, secularism, social harmony, international goodwill, moral building and “desh bhakti” (patriotism) have been included among the objectives of universities under the UPPUO.With the UPPOU, all private universities in UP, including the 27 existing ones, would come under an umbrella act. Currently, the private universities in the State have been set up and are running through separate acts and sanctions.However, the umbrella act would override all the acts as a “controlling body” to monitor and regulate the private varsities, said Sidharth Nath Singh, a Cabinet minister.The new system would look to bring uniformity to the fee structure, quality of education, implementation of the UGC guidelines and would attempt to “introduce the best practices of international universities,” said Mr. Singh.Among the proposals are that a minimum of 75% of teachers appointed to the private universities would be permanent and not contractual and their quality would be monitored online, Mr. Singh said.A university in a city would need to have a minimum land space of 20 acre while in rural areas they would need to be spread over 50 acre. The existing 27 universities have one year to implement the new changes.last_img read more

Mayookha Johny, Ram Singh Yadav and Renjith Maheswary told to undergo fitness trials

first_imgThe selection committee of the Athletics Federation of India (AFI) has raised questions regarding the fitness of three of the 14 track and field athletes who have qualified for the London Olympics.The athletes in question are triple jumpers Mayookha Johny and Renjith Maheshwary and marathoner Ram Singh Yadav.The AFI selection committee met on Monday, which was also the last day for qualification, to decide the team for the Olympics.AFI secretary general CK Valson said that the three athletes will have to undergo fitness tests to prove that they are in good enough condition to compete at the Olympics.The reason that the selection committee asked only three athletes to undergo fitness tests was because Mayookha, Renjith and Ram Singh have not competed in the recent past and hence, the selectors wanted to make sure they are fully fit.”Besides Ram Singh, Mayookha and Renjith have also been asked to prove their fitness. The fitness test will be trials so that the athletes can prove that they are fit to compete at the Olympics,” Valson told Mail Today.”The government observer pointed out that these athletes have not competed for quite some time and therefore, it was necessary that we do not send unfit athletes. Their form and fitness needs to be assessed and we have decided to conduct these trials,” he added.Ram Singh’s coach KS Mathew has given July 22 as the date for his ward’s trial that will be conducted in Bangalore, while Renjith and Mayookha and Renjith, both of whom are preparing for the Olympics abroad, have also been communicated about the trials.advertisementMayookha qualified for the Olympics in July last year with a national record effort of 14.11m. However, not much has been heard of her since then, although she did participate in a few competitions and has been confined to her base in Germany.Renjith is in Italy and not much has been heard of him either. His leap of 16.85m at the Federation Cup in June this year secured him an Olympic berth but the federation is not sure about his progress in the last few months.May was the last when he competed in Chonburi during the Asian Grand Prix in Thailand.Out of the three, only Ram Singh is in India and is undergoing high-altitude training in Ooty. However, on Tuesday, his coach KS Mathew received a couple of phone calls from the AFI top brass who asked them to decide on a date for the trial.”I was told that Ram Singh will have to undergo a fitness trial. We have agreed to undergo the trial on July 22 in Bangalore but that will surely affect our training programme,” Mathews told Mail Today.He added that Sports Authority of India (SAI) officials often visit his training camp and have never questioned Ram Singh’s fitness.In fact, SAI officials came as recently as July 1-2 to assess his training.”We have spoken to the coaches with whom they (Mayookha and Renjith) are training and we have figured out a mechanism to conduct their trials as well,” said Valson.The athletes are scheduled to reach London in batches as they are currently training in various countries at the moment.last_img read more